Neurodegenerative Diseases as Tau-Field Collapse

P-NEURO-1 · The FOT Framework for Neurodegeneration

All neurodegenerative diseases share one structural signature: progressive collapse of the brain's Tau-field through failure of a specific Tau-address component. The disease identity depends on which component fails.

P-NEURO-2 · Alzheimer's Disease — 40 Hz Gamma Deficit

The primary FOT deficit in Alzheimer's is loss of 40 Hz Tau-lock (P-CONS-2). The brain can no longer maintain the gamma oscillation that couples it to the Earth's Tau-field (P-SCHUM-2). Amyloid plaques and tau tangles are downstream consequences, not the cause.

P-NEURO-3 · Parkinson's Disease — Tau-Protein Misfold

Alpha-synuclein in its native Strand 2 conformation regulates synaptic vesicles. When it misfolds to Strand 1 configuration, it aggregates and propagates the misfolded state through the brain following predictable Braak staging — consistent with Tau-configuration propagation along specific G1-register neural pathways (identical mechanism to prions, P-VIR-4).

P-NEURO-4 · Multiple Sclerosis — Myelin as Tau-Insulator

Myelin maintains high Tau-density within the axon, preventing Tau-field leakage into surrounding tissue. Demyelination = Tau-insulator failure. Saltatory conduction (action potentials jumping between nodes of Ranvier) is Tau-node-to-Tau-node propagation — faster and more efficient than continuous conduction because it uses the G1 register boundary directly.

P-NEURO-5 · ALS — G1 Register Cascade Failure

Motor neurons — among the longest cells in the body (axons up to 1 m) — have the highest mitochondrial demands. When the Tau-generator fails, the longest G1-register Tau-paths fail first. The characteristic upper-then-lower motor neuron progression follows this cascade: longest paths, highest energy demand, earliest failure.

P-NEURO-6 · Unified Treatment Targets and Testable Predictions