The biology
In the frog Xenopus the ribosome's parts are made out of parallel: 5S RNA first, stored in particles, then the other rRNAs and proteins on demand. The genome carries about 100,000 copies of the 5S gene, and rather than carry as many large rRNA genes it selectively amplifies the few hundred rRNA genes just before it needs them. A zinc-finger factor both activates the 5S gene and binds the 5S product — feedback storage.
A gene that senses its own product
The factor that reads the 5S gene also binds the 5S RNA it makes — so the gene senses its own product and holds its output steady. This is dΣΤ homeostasis in a single coordinate: the field conserving the balance of what it produces, exactly the change-not-level sensing that reappears in the bacterium's behaviour (Paper 22). The 100,000 5S copies are address space held in reserve; amplification is the field instancing more of a coordinate precisely when it is needed.
Where this departs from current science
| Current science says | The Force of Time says |
|---|---|
| TFIIIA feedback is autoregulation by product binding. | It is dΣΤ homeostasis in a single gene — the coordinate holding its output balanced. |
| Gene amplification is a copy-number expedient. | It is the field instancing more of a coordinate on demand — address space held in reserve. |
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This paper, and any information drawn from it, may be used freely provided the reference attribution to Stephen Daubney and The Daubney Foundation is recognised.