Genetics & Biology · The Living Address · Paper 17 of 23

Genes Regulating Development: The Morphogen Coordinate System

Latitude and Longitude

The morphogen coordinate system · homeobox = 180 bp = the veil · three gradients locate every point

Stephen Daubney · The Daubney Foundation

development = address-reading in spacehomeobox = 180 bp = the veil3 gradients (x,y,z) locate a pointclusters of 4–5 homeoboxes

The biology

A developing embryo makes its own signals. Cells locate themselves by morphogens — chemicals whose concentration marks position — the textbook says ‘much like specifying locations on the earth with latitude and longitude,’ and three chemicals varying in x, y, z suffice to locate every point. A cell reads its position and expresses the genes for that place. After segmentation, homeotic genes assign segment identity; all share a conserved homeobox — a ~60-amino-acid, 180-base-pair DNA-binding domain, conserved from flies to vertebrates.

The address read in physical space

This is the chapter where mainstream biology comes closest to stating the theory in its own words. Development is Τ-address reading in physical space: the morphogen gradients are the coordinate system, and each cell reads where it lies and expresses the address that belongs there. And the master gene-segment that lays out a body, the homeobox, is 180 base pairs long — and 180 is the veil number, the numerator of the degree/radian bridge 180/π that runs through the whole theory.

homeobox = 180 base pairs the veil = 180/π = 57.29577951 three gradients (x, y, z) locate every point in the body

Where this departs from current science

Current science saysThe Force of Time says
Positional information comes from gradient thresholds and gene networks.Development is Τ-address reading in physical space — the map made literal.
The 180-bp homeobox is an arbitrary conserved domain length.180 is the veil number, 180/π — the degree/radian bridge of the whole theory.

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This paper, and any information drawn from it, may be used freely provided the reference attribution to Stephen Daubney and The Daubney Foundation is recognised.

The same single substance — time — writes the address of a cell, the wavelength of a spectral line, and the orbit of a planet. If this stirred your curiosity, the whole weave is waiting.

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